Our research focuses on the mechanics of biological systems at the cellular, intracellular, and molecular level. We develop new techniques, mainly based on micropipettes coupled to microscopy. We also like to artistically illustrate cellular processes.
Recent Publications
Adv Healthc Mater. 2025 Dec 12:e03250.Lenzi E, Vertti-Quintero N, Husson J, Bulteau AL, Nizard C, Pays K, Sart S, Baroud CN. Spherical Skin Model: Stratified Co-Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening. doi: 10.1002/adhm.202503250.
Cell Reports Physical Sciences (journal cover) Volume 6, Issue 12102997, December 17, 2025
Stiffening cells with light. Eva Gonzalez, Jana El Husseiny, Finn Bastian Molzahn, Tiffany Campion, Hadrien Jalaber, Stéphanie Dogniaux, Pierre-Henri Puech, Oliver Nüsse, Laure Gibot, and Julien
Husson.
Communication by Ecole
polytechnique.
bioRxiv 2025.01.30.635790; doi: 10.1101/2025.01.30.635790.
Stiffening cells with light. Eva Gonzalez, Jana El Husseiny, Finn Bastian Molzahn, Tiffany Campion, Hadrien Jalaber, Stéphanie Dogniaux, Pierre-Henri Puech, Oliver Nüsse, Laure Gibot, and Julien Husson.
Stiffness fluctuations in T cells. Molzahn, F.B., Husson, J. Stiffness fluctuations in T cells. Eur. Phys. J. E 48, 75 (2025). https://doi.org/10.1140/epje/s10189-025-00540-0
arXiv:2511.18002v1 [cond-mat.soft] 22 Nov 2025. Deformation and organization of droplet-encapsulated soft beads.
STAR Protocols, 2025; doi: 10.1016/j.xpro.2025.104234. Protocol for quantifying coccidian parasite mechanics and rupture force using advanced micromanipulation-based piercing. Jana El Husseiny, Pierre-Henri Puech, Aurélien Dumètre, and Julien Husson.
Biophysical Journal, 2024; 123(2):210-220. doi: 10.1016/j.bpj.2023.12.008. Quantifying both viscoelasticity and surface tension: why sharp tips overestimate cell stiffness. Olga Markova, Christophe Clanet, Julien Husson.
Phys. Rev. Lett. 130, 064001 (2023). Clogging of a rectangular slit by a spherical soft particle. Charles Paul Moore, Julien Husson, Arezki Boudaoud, Gabriel Amselem, and Charles N. Baroud. [HAL archive]
Methods in Molecular Biology (MIMB, volume 2600) DOI:10.1007/978-1-0716-2851-5_1, 2023. Measuring Cell Mechanical Properties Using Microindentation. Julien Husson. [HAL archive]